Archive for September, 2010


Somatotropin, also commonly referred to as human growth hormone (HGH), is a hormone that is produced in the human body and secreted into the blood by the somatotrope cells of the anterior pituitary gland. It is a single-chain protein that is composed of 191 amino acids. HGH secretion has many direct and indirect effects on the human body.  Because HGH stimulates the liver’s production of insulin-like growth factor (IGF-1), the effects of both HGH and IGF-1 are listed below.

The synthetic version of Human Growth Hormone is called Somatropin (191 amino acid sequence growth hormone). It is identical to the body’s own HGH. However that is not the case for Somatrem (192 amino acid sequence growth hormone).

Direct and Indirect Effects of Somatotropin on the Human Body:

  • Stimulates division and multiplication of the chondrocytes of cartilage
  • Increases both calcium retention and the mineralization of bones
  • Stimulates cell growth in every organ of a human body
  • Increases metabolism
  • Repairs damaged cells
  • Induces protein synthesis
  • Decreases protein degradation
  • Stimulates the immune system
  • Promotes lipolysis
  • Increases glucose transport

In the body, Somatotropin is at its highest levels in children and during puberty, stimulating the growth of the body during those ages. After puberty, the level of growth hormone secretion declines and continues to do so as a person ages.

Growth hormone deficiency (GHD) is a disease in which a person’s pancreas fails to produce an adequate amount of normal endogenous growth hormone. In children, this results in short stature and growth failure. In adults, GHD causes deficiencies of strength, energy, and bone mass. 
GHD can be treated in both children and adults with Somatropin.  However, to treat conditions of height, a child must be treated before the growth plates (epiphyses) at the ends of long bones have fully matured and closed.

Healthy adults most commonly use Human Growth Hormone for Anti Aging, Body Building and Fat Loss purposes.